The USS Aylwin (DD-355) was a member of the Farragut-class destroyer family, a class of eight 1,365-ton destroyers built by the U.S. Navy following World War I. On April 29, 1916, Congress authorized their construction, along with the Porter-class destroyers, but funding was substantially delayed. The USS Aylwin, the third ship of the U.S. Navy to be named for Lieutenant John Cushing Aylwin (1778–1812), was laid down at the Philadelphia Navy Yard on September 23, 1933, launched on July 10, 1934, sponsored by Miss Elizabeth M. Farley, Postmaster General James Farley's 11-year-old daughter, and commissioned on March 1, 1935. The ship received 13 combat stars for her service during World War II. After passing the canal for the final time on September 20, 1945, the USS Aylwin arrived in New York City on September 25, 1945. The USS Aylwin was decommissioned on 16 October 1945 at the New York Navy Yard and struck from the Navy List on 1 November 1945. On 20 December 1946, her hull was sold and sent to George N. Nutman, Inc. of Brooklyn, New York, and scrapped by 2 September 1948.

Introduced in Update 1.79 "Project X", the USS Aylwin's firepower exceeds that of the previous Clemson-class destroyers. The fearsome armaments of the USS Aylwin can destroy ships at medium to close range. Unfortunately, due to the relatively low velocity of her guns, players using the USS Aylwin will find it more difficult to land shots at ranges greater than 6 km. At closer ranges, her absence of anti-fragmentation armour significantly harms the ship for being caught in enemy gunfire, as an escape can take time. As a result, the USS Aylwin should use her high rate of fire and powerful weapons at medium range to hold cap zones and assist more protected friends in pressing higher. Furthermore, opponents may be less inclined to attack the USS Aylwin as the anti-air defence is adequate. Nonetheless, air-dropped torpedoes and low-flying bombers flying close to the water's surface must be avoided or prioritised.